
The NAD Expert: This Is the Ideal Level for Your Cells | Dr. Jin Xiong She
In this video, Dr. Jin Xiong She, an expert on NAD+ and founder of Genfinity Precision Medicine, discusses the latest research on NAD levels in the human body. He debunks common misconceptions and provides practical advice for optimizing NAD levels.
Key Findings on NAD Research
- Age-Related Decline: NAD levels do not decline linearly with age; the sharpest drop occurs between the ages of 20 and 30. After that, the decline is minimal.
- Health Status and Ethnicity: Individuals with health issues and certain ethnic groups (e.g., Asians) often have lower NAD levels than healthy Caucasians.
- Misinterpretation of Studies: Dr. She criticizes the study by Yansen et al., which found no age-related decline in NAD levels, arguing it is flawed due to its narrow age range and overgeneralization.
Methods to Boost NAD Levels
- Nicotinamide (NAM): Ineffective as an NAD precursor—only about a 10% average increase, with 70% of people showing no change.
- NMN and NR: More effective precursors—1,000 mg of NMN or NR can increase NAD levels by 40–50%.
- Optimized Formulations: Dr. She's patented blend of NMN and other ingredients can boost NAD levels by 116% (powder form) or 150% (special formula).
- NAD IV Infusions: Provide a short-term spike in blood NAD but no sustained increase in intracellular NAD—therefore unsuitable for longevity or performance enhancement.
The Ideal NAD Level
- Optimal Range: Between 55 and 80 micromolar (measured in blood using Genfinity's method). A level above 40 micromolar is considered a minimum; values over 100 micromolar are unnecessary and may be harmful (increased risk of vascular inflammation, e.g., from high niacin doses).
- Testing Recommendation: Take a baseline test before starting supplementation, then retest after 3–4 weeks to assess effectiveness. NAD levels drop by about 3% per day without supplementation.
Additional Tips
- The microbiome and lifestyle can influence NAD levels, but data are still incomplete.
- Dr. She emphasizes: "NAD is a micronutrient—you need to supply it regularly, like vitamins."






